Non-Small Cell Lung CancerThe information on this site is intended for US healthcare professionals only.
Play storyWhen Vikki was diagnosed with unresectable Stage 3 non-small cell lung cancer (NSCLC), her life of caring for others flipped upside down. Through her IMFINZI® (durvalumab) after chemoradiation therapy treatment, she learned to prioritize and care for herself—something she carries with her to this day.
Play storyVikki: I make space for my daughter first. I make space every day for my animals who I dearly love. I’m Vikki. I’m 74 years old. I'm retired but I work two jobs. I've got a multitude of animals at home that fill my life, and a beautiful daughter. I've always been the keeper of everyone. When my mother passed, I said, “Mom, don't worry about a thing. I've got the family. I'll take care of them.” And that was my goal. Now it's my turn. I’m gonna take care of me. That's where I am right now. My main doctor, my primary doctor kept watching a nodule in my lung. But he never went as far to get a CAT scan. So then they thought I had a blood clot in my leg. So they did a CAT scan and found out it was a malignant tumor. I think I was in kind of a fog. They did a biopsy. Found out it was something that they couldn’t remove. The conversation was real clouded, you know. I wasn't grasping what he was saying. The next meeting I was better ‘cause then he said, “Okay, we're going to do chemo, radiation, and the therapy.” And very emotional, still emotional, so. But… I'm real headstrong, and I had to be strong for my family.
VOICEOVER: IMFINZI® (durvalumab) is a prescription medicine used to treat adults with a type of lung cancer called non-small cell lung cancer (NSCLC). IMFINZI may be used when your NSCLC has not spread outside your chest, cannot be removed by surgery, and has responded or stabilized with initial treatment with chemotherapy that contains platinum, given at the same time as radiation therapy.
Vikki: With using the drug IMFINZI, my daughter was more concerned because I think during that time, being so far within the treatments, like the chemo, the radiation, and then starting IMFINZI once a month. But she said, “Mom, it's all for a good cause. You gotta keep going forward.” So I'm just gonna go for it. And the nurses there, they were so supportive of me. They just make you feel family. I keep going back to the same word. It was my safe zone. I think people need to not feel sorry for themselves, which is hard to do, because I know I did it. ‘Cause it's the “why me” thing. First of all, find a doctor that they believed in or they felt safe with. I think that's one of the biggest things. But you gotta have faith in your doctor. I got a little house, got a wonderful family with my pets, and a good doctor. I don't think much about cancer. I’m living my life day to day. I'm happy with who I am, where I am, who I'm with, what I can give.
VOICEOVER:
IMPORTANT SAFETY INFORMATION
What is the most important information I should know about IMFINZI® (durvalumab)?
IMFINZI is a medicine that may treat certain cancers by working with your immune system. IMFINZI can cause your immune system to attack normal organs and tissues in any area of your body and can affect the way they work. These problems can sometimes become severe or life-threatening and can lead to death. You can have more than one of these problems at the same time. These problems may happen anytime during treatment or even after your treatment has ended.
Call or see your healthcare provider right away if you develop any new or worsening signs or symptoms, including:
Lung problems: cough, shortness of breath, and chest pain
Intestinal problems: diarrhea (loose stools) or more frequent bowel movements than usual; stools that are black, tarry, sticky, or have blood or mucus; and severe stomach-area (abdomen) pain or tenderness
Liver problems: yellowing of your skin or the whites of your eyes, severe nausea or vomiting, pain on the right side of your stomach area (abdomen), dark urine (tea colored), and bleeding or bruising more easily than normal
Hormone gland problems: headaches that will not go away or unusual headaches; eye sensitivity to light; eye problems; rapid heartbeat; increased sweating; extreme tiredness; weight gain or weight loss; feeling more hungry or thirsty than usual; urinating more often than usual; hair loss; feeling cold; constipation; your voice gets deeper; dizziness or fainting; and changes in mood or behavior, such as decreased sex drive, irritability, or forgetfulness
Kidney problems: decrease in your amount of urine, blood in your urine, swelling of your ankles, and loss of appetite
Skin problems: rash; itching; skin blistering or peeling; painful sores or ulcers in mouth or nose, throat, or genital area; fever or flu-like symptoms; and swollen lymph nodes
Pancreas problems: pain in your upper stomach area (abdomen), severe nausea or vomiting, and loss of appetite
Problems can also happen in other organs and tissues. These are not all of the signs and symptoms of immune system problems that can happen with IMFINZI. Call or see your healthcare provider right away for any new or worsening signs or symptoms, which may include: Chest pain, irregular heartbeats, shortness of breath or swelling of ankles; confusion, sleepiness, memory problems, changes in mood or behavior, stiff neck, balance problems; tingling, numbness or weakness of the arms or legs; double vision, blurry vision, sensitivity to light, eye pain, changes in eye sight; persistent or severe muscle pain or weakness, muscle cramps, joint pain, joint stiffness or swelling; and low red blood cells and bruising
Infusion reactions that can sometimes be severe or life-threatening. Signs and symptoms of infusion reactions may include: chills or shaking, itching or rash, flushing, shortness of breath or wheezing, dizziness, feel like passing out, fever, and back or neck pain
Rejection of a transplanted organ or tissue. Your healthcare provider should tell you what signs and symptoms you should report and monitor you depending on the type of organ or tissue transplant that you have had
Complications, including graft-versus-host disease (GVHD), in people who have received a bone marrow (stem cell) transplant that uses donor stem cells (allogeneic). These complications can be serious and can lead to death. These complications may happen if you underwent transplantation either before or after being treated with IMFINZI. Your healthcare provider will monitor you for these complications
Getting medical treatment right away may help keep these problems from becoming more serious. Your healthcare provider will check you for these problems during your treatment with IMFINZI. Your healthcare provider may treat you with corticosteroid or hormone replacement medicines. Your healthcare provider may also need to delay or completely stop treatment with IMFINZI if you have severe side effects
Before you receive IMFINZI, tell your healthcare provider about all of your medical conditions, including if you:
Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
What are the possible side effects of IMFINZI?
IMFINZI can cause serious side effects (see above).
The most common side effects of IMFINZI when used alone in adults with non-small cell lung cancer (NSCLC) that cannot be removed by surgery include cough, feeling tired, inflammation in the lungs, upper respiratory tract infections, shortness of breath, and rash.
Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of IMFINZI. Ask your healthcare provider or pharmacist for more information.
Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of AstraZeneca prescription drugs by calling 1-800-236-9933.1-800-236-9933. If you prefer to report these to the FDA, call 1-800-FDA-1088.1-800-FDA-1088.
What is IMFINZI?
IMFINZI is a prescription medicine used to treat adults with a type of lung cancer called non-small cell lung cancer (NSCLC). IMFINZI may be used when your NSCLC has not spread outside your chest, cannot be removed by surgery, and has responded or stabilized with initial treatment with chemotherapy that contains platinum, given at the same time as radiation therapy.
It is not known if IMFINZI is safe and effective in children.
Please see full Prescribing Information, including Patient Information (Medication Guide) for IMFINZI at IMFINZI.com.
When Vikki was diagnosed with unresectable Stage 3 non-small cell lung cancer (NSCLC), her life of caring for others flipped upside down. Through her IMFINZI® (durvalumab) after chemoradiation therapy treatment, she learned to prioritize and care for herself—something she carries with her to this day.
Non-Small Cell Lung Cancer
Small Cell Lung Cancer
Unresectable Hepatocellular Carcinoma
Non-Small Cell Lung Cancer
Small Cell Lung Cancer
Unresectable Hepatocellular CarcinomaIMFINZI and IMJUDO are medicines that may treat certain cancers by working with your immune system. IMFINZI and IMJUDO can cause your immune system to attack normal organs and tissues in any area of your body and can affect the way they work. These problems can sometimes become severe or life-threatening and can lead to death. You can have more than one of these problems at the same time. These problems may happen anytime during treatment or even after your treatment has ended.
IMFINZI and IMJUDO are prescription medications that may treat certain cancers.
IMFINZI is used to treat adults with a type of lung cancer called NSCLC.
IMFINZI is used to treat adults with a type of lung cancer called SCLC.
IMFINZI is used in combination with chemotherapy medicines gemcitabine and cisplatin to treat adults with a type of cancer called BTC, including cancer of the bile ducts (cholangiocarcinoma) and gallbladder cancer, when your BTC has spread to nearby tissues (locally advanced), or has spread to other parts of the body (metastatic).
IMFINZI is used in combination with IMJUDO to treat adults with a type of liver cancer that cannot be removed by surgery (unresectable hepatocellular carcinoma or uHCC).
IMFINZI is used in combination with the chemotherapy medicines carboplatin and paclitaxel followed by IMFINZI alone to treat adults with a type of uterine cancer called endometrial cancer that has spread (advanced) or has come back (recurred), and a laboratory test shows that your tumor is mismatch repair deficient (dMMR).
IMFINZI is used in combination with Bacillus Calmette-Guérin (BCG) to treat a type of bladder cancer called high-risk non-muscle-invasive bladder cancer (NMIBC) that has not spread into the muscle layer of the bladder, when you have not had prior treatment with BCG.
IMFINZI may be used in combination with the chemotherapy medicines gemcitabine and cisplatin (neoadjuvant treatment) prior to surgical removal of your bladder followed by IMFINZI alone after surgery (adjuvant treatment) to treat a type of bladder cancer called muscle- invasive bladder cancer (MIBC) that has spread into the muscle layer of the bladder but not to other parts of the body.
IMFINZI is used in combination with FLOT prior to and after surgery followed by IMFINZI alone to treat adults with a type of stomach cancer called gastric cancer (GC) or gastroesophageal junction adenocarcinoma (GEJC) that can be removed by surgery.
It is not known if IMFINZI and IMJUDO are safe and effective in children.
Getting medical treatment right away may help keep these problems from becoming more serious. Your healthcare provider will check you for these problems during your treatment with IMFINZI and IMJUDO. Your healthcare provider may treat you with corticosteroid or hormone replacement medicines. Your healthcare provider may also need to delay or completely stop treatment with IMFINZI and IMJUDO if you have severe side effects
Before you receive IMFINZI and IMJUDO, tell your healthcare provider about all of your medical conditions, including if you:
Females who are able to become pregnant:
Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
The most common side effects of IMFINZI when used alone in adults with NSCLC that cannot be removed by surgery include cough, feeling tired, inflammation in the lungs, upper respiratory tract infections, shortness of breath, and rash.
The most common side effects of IMFINZI when used with platinum-containing chemotherapy in adults with NSCLC that can be removed by surgery include low red blood cells (anemia), nausea, constipation, feeling tired, muscle or bone pain, and rash.
The most common side effects of IMFINZI when used in combination with IMJUDO and platinum-containing chemotherapy in adults with metastatic NSCLC include nausea, feeling tired or weak, muscle or bone pain, decreased appetite, rash, and diarrhea.
The most common side effects of IMFINZI when used alone in adults with limited-stage small cell lung cancer (LS-SCLC) include inflammation in the lungs and feeling tired or weak.
The most common side effects of IMFINZI when used with etoposide and either carboplatin or cisplatin in adults with extensive-stage small cell lung cancer (ES-SCLC) include nausea, feeling tired or weak, and hair loss.
The most common side effects of IMFINZI when used with gemcitabine and cisplatin in adults with biliary tract cancer (BTC) include feeling tired, nausea, constipation, decreased appetite, stomach (abdominal) pain, rash, and fever.
The most common side effects of IMFINZI and IMJUDO in adults with unresectable hepatocellular carcinoma (uHCC) include rash, diarrhea, feeling tired, itchiness, muscle or bone pain, and stomach (abdominal) pain.
The most common side effects of IMFINZI when used with carboplatin and paclitaxel in adults with endometrial cancer include inflammation of the nerves causing numbness, weakness, tingling or burning pain of the arms and legs; muscle or bone pain; nausea; hair loss; feeling tired; stomach (abdominal) pain; constipation; rash; decreased level of magnesium in the blood; increased liver function tests; diarrhea; vomiting; cough; decreased level of potassium in the blood; shortness of breath; headache; and increased level of alkaline phosphatase in the blood.
The most common side effects of IMFINZI when used with BCG in adults with high-risk non-muscle-invasive bladder cancer include increased liver function tests, urinary tract infection, increased level of potassium in blood, pain or discomfort with urination, decreased red blood cells (anemia), blood in urine, increased level of creatinine in the blood, muscle or bone pain, decreased lymphocyte counts, urinate more often, decreased level of sodium in the blood, feeling tired, rash, and fever.
The most common side effects of IMFINZI when used with gemcitabine and cisplatin in adults with muscle-invasive bladder cancer (MIBC) include decreased red blood cells (anemia), decreased white blood cells, increased level of creatinine in the blood, decreased level of sodium in the blood, nausea, increased liver function tests, decreased level of calcium in the blood, decreased blood platelet counts, feeling tired, increased level of potassium in the blood, decreased lymphocyte counts, constipation, decreased level of magnesium in the blood, decreased appetite, increased level of alkaline phosphatase in the blood, rash, fever, diarrhea, vomiting, and stomach (abdominal) pain.
The most common side effects of IMFINZI when used with fluorouracil, leucovorin, oxaliplatin, and docetaxel (FLOT) in adults with gastric cancer (GC) or gastroesophageal junction adenocarcinoma (GEJC) that can be removed by surgery include: diarrhea; nausea; inflammation of the nerves causing numbness, weakness, tingling, or burning pain of the arms and legs; feeling tired; hair loss; decreased appetite; rash; stomach (abdominal) pain; vomiting; muscle and joint pain; fever; and pain and sores in the mouth.
Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of IMFINZI and IMJUDO. Ask your healthcare provider or pharmacist for more information.
Call your doctor for medical advice about side effects. You may report side effects related to AstraZeneca products. If you prefer to report these to the FDA, either visit www.FDA.gov/medwatch or call 1-800-FDA-1088.
Call your doctor for medical advice about side effects. You may report side effects related to AstraZeneca products. If you prefer to report these to the FDA, either visit www.FDA.gov/medwatch or call 1-800-FDA-1088.
IMFINZI and IMJUDO are prescription medications that may treat certain cancers.
IMFINZI is used to treat adults with a type of lung cancer called NSCLC.
IMFINZI is used to treat adults with a type of lung cancer called SCLC.
IMFINZI is used in combination with chemotherapy medicines gemcitabine and cisplatin to treat adults with a type of cancer called BTC, including cancer of the bile ducts (cholangiocarcinoma) and gallbladder cancer, when your BTC has spread to nearby tissues (locally advanced), or has spread to other parts of the body (metastatic).
IMFINZI is used in combination with IMJUDO to treat adults with a type of liver cancer that cannot be removed by surgery (unresectable hepatocellular carcinoma or uHCC).
IMFINZI is used in combination with the chemotherapy medicines carboplatin and paclitaxel followed by IMFINZI alone to treat adults with a type of uterine cancer called endometrial cancer that has spread (advanced) or has come back (recurred), and a laboratory test shows that your tumor is mismatch repair deficient (dMMR).
IMFINZI is used in combination with Bacillus Calmette-Guérin (BCG) to treat a type of bladder cancer called high-risk non-muscle-invasive bladder cancer (NMIBC) that has not spread into the muscle layer of the bladder, when you have not had prior treatment with BCG.
IMFINZI may be used in combination with the chemotherapy medicines gemcitabine and cisplatin (neoadjuvant treatment) prior to surgical removal of your bladder followed by IMFINZI alone after surgery (adjuvant treatment) to treat a type of bladder cancer called muscle- invasive bladder cancer (MIBC) that has spread into the muscle layer of the bladder but not to other parts of the body.
IMFINZI is used in combination with FLOT prior to and after surgery followed by IMFINZI alone to treat adults with a type of stomach cancer called gastric cancer (GC) or gastroesophageal junction adenocarcinoma (GEJC) that can be removed by surgery.
It is not known if IMFINZI and IMJUDO are safe and effective in children.
Please see Full Prescribing Information including Medication Guide for IMFINZI and IMJUDO.
IMFINZI and IMJUDO are medicines that may treat certain cancers by working with your immune system. IMFINZI and IMJUDO can cause your immune system to attack normal organs and tissues in...
IMFINZI is a medicine that may treat...

IMFINZI and IMJUDO are prescription medications that may treat certain cancers.
IMFINZI is used to treat adults with a type of lung cancer called NSCLC...
IMFINZI is a medicine that may treat certain cancers by working with your immune...
IMFINZI is a medicine that may treat certain cancers by working with your immune...
