To understand how IMFINZI works, it's important to understand the key players. They are:
When cancer cells appear in your body, your immune system works to recognize and attack them.
PD-L1 is a protein that disguises cancer cells from the immune system.
IMFINZI works by blocking PD-L1 to remove the disguise…
…so your immune system is better able to find and attack these cancer cells. There is a chance that IMFINZI may affect healthy cells, too.
IMFINZI is an immunotherapy—a type of cancer treatment that works with your immune system to find and attack cancer. There is a chance that IMFINZI may affect healthy cells, too.
What is the most important information I should know about IMFINZI?
IMFINZI is a medicine that may treat a type of cancer in the bladder and urinary tract by working with your immune system.
In some patients, IMFINZI can cause the immune system to attack normal organs and tissues and can affect the way they work. These problems can sometimes become serious or life-threatening and can lead to death.
Call or see your healthcare provider right away if you develop any symptoms of the following problems or if these symptoms get worse:
Getting medical treatment right away may help keep these problems from becoming more serious. Your healthcare provider will check you for these problems during your treatment with IMFINZI. Your healthcare provider may treat you with corticosteroid or hormone replacement medicines. Your healthcare provider may delay or completely stop treatment with IMFINZI if you have severe side effects.
Before you receive IMFINZI, tell your healthcare provider about all of your medical conditions, including if you:
Tell your healthcare provider about all the medicines you take. This includes prescription and over-the-counter medicines, vitamins, and herbal supplements.
What are the possible side effects of IMFINZI?
IMFINZI can cause serious side effects (see above).
The most common side effects include:
Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of IMFINZI. Ask your healthcare provider or pharmacist for more information.
IMFINZI™ (durvalumab) is a prescription medicine used to treat a type of cancer in the bladder and urinary tract called urothelial carcinoma.
IMFINZI may be used when:
It is not known if IMFINZI is safe and effective in children.
IMFINZI was FDA approved based on a clinical study that measured how many patients responded and how long they responded. The study is ongoing to confirm clinical benefit.