@font-face {
    font-family: 'din-2014-narrow';
    src: url('/content/dam/website-services/us/498-rwd-imfinzi-com/stage-4-nsclc/fonts/DIN2014_Narrow.woff2') format('woff2'),
         url('/content/dam/website-services/us/498-rwd-imfinzi-com/stage-4-nsclc/fonts/DIN2014_Narrow.woff') format('woff');
    font-weight: normal;
    font-style: normal;
    font-display: swap;
}

.modal-open .modal{
        background: #000000cc;
}
.cholangiocarcinoma #empoverlay #exitdialog {
  /*  border-radius: 8px 50px 8px 50px !important;*/
    width:624px;
    padding: 33px;
}

.cholangiocarcinoma #exitdialog div.rich-text>p {
    color: #333;
    font-family: "Filson Pro";
    font-size: 18px;
    font-style: normal;
    font-weight: 425;
    line-height: 24px;
    margin:0 0 32px;
}
.siteexit-title {
    margin-bottom: 32px;
}

.blue-callout-head {
    background-color: #006666;
    color: #FFFFFF;
    font-family: solex, sans-serif;
    font-weight: 700;
    max-width: 1132px;
    margin: 0 auto;
    border-radius: 8px 30px 0 0;
    margin-bottom: 0;
    padding: 10px 10px 14px 22px;
    font-size: 28px;
    line-height: 32px;
}

.carcinoma-subhead {
    color: #006666;
    font-family: "solex", sans-serif;
    font-weight: 700;
}

.carcinoma-bodycopy {
    font-family: "din-2014", sans-serif;
    font-weight: 400;
  /*color: #525252;*/
    color: #333333;
    font-size: 22px;
    line-height: 30px;
}

.btc-copy {
    font-family: "din-2014", sans-serif;
    font-weight: 400;
    color: #333333;
    font-size: 22px;
    line-height: 30px;
}

.end-page-callout h5 span {
    z-index: 0;
    position: relative;
    display: inline-block;
}

.end-page-callout h5 span:after {
   /* content: "";
    border-bottom: 5px solid #D8EA00;
    width: 103%;
    position: absolute;
    bottom: 20px;
    left: -5px;
    z-index: -1;*/
}

.subhead {
    font-size: 32px;
    color: #006666;
    font-family: "solex", sans-serif;
    font-weight: 700;
}

.inner-copy {
    font-family: din-2014, sans-serif;
    font-weight: 400;
    font-size: 18px;
    line-height: 26px;
    color: #555555;
}

.page-heading {
    font-family: "solex", sans-serif;
    font-weight: 700;
    color: #006666;
    margin: 0;
}

.head-copy {
    font-family: "din-2014", sans-serif;
    font-weight: 400;
    color: #333333;
    font-size: 22px;
    line-height: 30px;
    margin-top: 9px;
    text-align: center;
}

.page-subhead {
    font-family: "solex", sans-serif;
    font-weight: 700;
    color: #006666;
    margin: 0;
    font-size: 28px;
    line-height: 32px;
}

/*US-83414 Updates starts here*/

.submenu-arrow {
    background: #fff;
    -webkit-appearance: none;
    -moz-appearance: none;
    appearance: none;
    border: 0;
    position: relative;
    right: 5px;
    top: 20px;
    padding: 0;
    z-index: 100;
}

.submenu-arrow span.navigation__arrow:after {
    content: "\e114";
    color: #9D2D33;
    font-family: "Glyphicons Halflings";
    font-style: normal;
    font-weight: 400;
    line-height: 1;
    -webkit-font-smoothing: antialiased;
    -webkit-text-stroke: 3px #fff;
    font-size: 21px;
}

button#resources__btn {
    right: 13px;
}

.submenu-arrow[aria-expanded="true"] span.navigation__arrow:after {
    content:"\e113";
}

.isi__head {
    margin-top: -10px;
    margin-bottom: 0;
}

.siteexit-title h2 {
    /*text-transform: uppercase;*/
    font-family: "Filson Pro";
    font-size: 30px;
    font-style: normal;
    font-weight: 800;
    line-height: 38px;
}
/*US-83414 Updates ends here*/
@media screen and (min-width: 992px) {
    .mobile-only{
		display: none!important;
    }
    .main_logo img {
        max-width: 326px;
    }
    .blue-callout-head {
        text-align: center;
    }
    a.sign-up-container.new-desktop-only:hover {
        text-decoration: none;
    }
    .carcinoma-subhead {
        line-height: 38px;
        font-size: 38px;
        letter-spacing: 0.38px;
    }
    .subhead {
        line-height: 39px;
        letter-spacing: 0.32px;
    }
    .page-heading {
        font-size: 38px;
        line-height: 48px;
        text-align: center;
        letter-spacing: 0.38px;
    }
    .page-subhead {
        font-size: 32px;
        letter-spacing: 0.32px;
        line-height: 39px;
        text-align: center;
    }
    .end-page-callout h5 span:after {
        bottom: 32px;
    }

    /*US-83414 Updates starts here*/
    .fullnavigation {
        position: relative;
    }
    
    a.sign-up-container.new-desktop-only {
        right: -94px;
    }

	.before-trtmt .list-of-infusions, 
	.during-trtmt .list-of-infusions, 
    .after-trtmt .list-of-infusions {
        padding-right: 20px;
    }
    
    li.fact-item.right-list--item {
        display: inline-flex!important;
        float: inherit;
        clear: both;
        width: 50%;
    }
    
    li.fact-item.left-list--item {
        width: 41.8%;
        float: left;
        clear: both;
    }

    .during-trtmt li.fact-item.right-list--item {
        width: 53%;
        margin-left: 50px;
    }
    
    .during-trtmt li.fact-item.left-list--item {
        width: 34%;
    }
    
    .during-trtmt li.fact-item.single-list--item {
        clear: both;
    }
    
    .preparing-for-infusions .before-trtmt-cont.during-trtmt.new-desktop-only .list-of-infusions ul:first-child,
    .preparing-for-infusions .before-trtmt-cont.after-trtmt.new-desktop-only .list-of-infusions ul:first-child{
        margin-right: 0;
    }

    .after-trtmt li.fact-item.left-list--item {
        width: 100%;
        margin-right: 8px;
    }

	.side-effects .bullet-flex {
        display: block!important;
    }

    .side-effects li.left-list--item {
        float: left;
        clear: both;
    }

    .side-effects .column-1 li.left-list--item {
        width: 48%;
        margin-right: 42px;
    }
    
    .side-effects .column-1 li.left-list--item:nth-child(6) {
        padding-right: 3px;
    }

    .side-effects .column-2 li.left-list--item {
        width: 47.9%;
        margin-right: 42px;
        margin-top: 0px!important;
    }
    
    .side-effects .column-2 li.right-list--item {
        padding-top: 10px;
    }

	.faqs .end-page-callout a.green-btn {
      /*  max-width: 290px; */
    }

	li.brochure a.last-menu-item {
        display: flex!important;
        flex-direction: row;
        padding-left: 10px!important;
        padding-right: 6px !important;
    }
    
    .navbar-nav li.brochure a.last-menu-item span{
        text-align: left;
    } 
    /*US-83414 Updates ends here*/

    /*li.about-imfinzi.submenu li.brochure span {
        display: none;
    }*/
    li.about-imfinzi.submenu li.brochure span.about-only {
        display: block;
    }
    li.treatment.submenu li.brochure span {
        display: block;
    }
    li.treatment.submenu li.brochure span.about-only {
        display: none;
    }
}

@media screen and (max-width: 991px) {
    .cholangiocarcinoma #exitdialog .close_icon img.close_exit {
        max-width: 18px;
        right: 22px;
    }
    .blue-callout-head {
        text-align: left;
        margin: 0 17px;
        padding: 16px 10px 18px 22px;
    }
    .pie h2.blue-callout-head {
        margin: 0;
    }
    .carcinoma-subhead {
        line-height: 32px;
        font-size: 36px;
    }
    .subhead {
        line-height: 36px;
        letter-spacing: 0.3px;
    }
    .page-heading {
        font-size: 32px;
        line-height: 36px;
        text-align: left;
    }
	.ask-doc-cont .page-heading{padding-top:20px;}
    .head-copy {
        text-align: left;
    }
    .page-subhead {
        font-size: 28px;
        line-height: 32px;
        letter-spacing: 0.32px;
    }

	/*US-83414 starts here*/
    a.mobile-sign-up-container.new-mobile-only:hover, a.mobile-sign-up-container.new-mobile-only:focus {
        color: #FFFFFF;
    }

	.submenu-arrow {
        background: #006666;
        border: 0;
        position: absolute;
        right: 17px;
        top: 17px;
    }
    
    .submenu-arrow span.navigation__arrow:after {
        color: #D7EA00;
        -webkit-text-stroke: 4px #006666;
        font-size: 30px;
    }
    
    li.submenu {
        position: relative;
    }
    
    button#resources__btn {
        right: 17px;
    }

	.navbar-toggle + a.navbar-brand {
        border: 1px solid;
        display: none;
    }

    .navbar-default button.navbar-toggle:focus {
        outline: 1px solid;
    }

    .preparing-for-infusions .width100.end-page-callout {
        height: auto;
        background-position: bottom;
    }
    
    .preparing-for-infusions .end-page-callout h5 {
        line-height: 33px;
    }

	/*.faqs .end-page-callout {
        height: 230px;
        background-position: bottom;
    }

    .faqs .end-page-callout h5 {
        line-height: 40px;
    }*/

	.side-effects .end-page-callout a.green-btn span::after {
        top: 5px;
    }
	/*US-83414 ends here*/
}

@media screen and (min-width: 768px) {
    .isi .row,
    .isi-remained,
    .isi-side-effects-container .side-effects-copy {
        max-width: 1132px;
    }
}

/*@media not all and (min-resolution:.001dpcm) { 
     @supports (-webkit-appearance:none) {
	  .Sticky_ISI p.clear.desktop_only{
		display: none !important;
	  }
}}*/   

/*US-83414 Updates starts here*/
@media screen and (min-width: 1140px){
    a.sign-up-container.new-desktop-only {
        right: -161px;
    }

    .after-trtmt li.fact-item.left-list--item {
        margin-right: 105px;
    }


    .before-trtmt-cont.during-trtmt.new-desktop-only ul > li.fact-item.right-list--item:nth-child(4) {
        margin-bottom: 38px;
    }
}
/*US-83414 Updates ends here*/